Searchable abstracts of presentations at key conferences in endocrinology

ea0092ps3-30-04 | Thyroid Physiology in Periphery & Development Basic | ETA2023

Thyroid hormone treatment counteracts pathological alterations in diabetic nephropathy and diabetic cardiomyopathy

Michele Lavecchia Angelo , Mantzouratou Polyxeni , Cerullo Domenico , Locatelli Monica , Conti Sara , Tironi Matteo , Sangalli Fabio , Corna Daniela , Zoja Carlamaria , Remuzzi Giuseppe , Xinaris Christodoulos

Diabetic nephropathy (DN) and cardiomyopathy (DC) are two major complications of diabetes that account for over two thirds of deaths among diabetic patients. Our previous studies have shown that thyroid hormone (TH) signalling – in addition to its critical role in physiological growth and organ development – plays similar roles in pathological conditions that encompass cellular dedifferentiation, cyto-architectural reorganization and compensatory growth. Though the r...